NAVIGATOR CHAT
DATABASE SEARCH
ChEMBL
ZINC
◈
Start with anything — a compound name, SMILES, disease, or question
Try: "what off-label uses does aspirin have?"
Or: "safer analogue of imatinib, less cardiac toxicity"
Or: "combine the BCR-ABL scaffold of imatinib with dasatinib selectivity"
Thinking…
◈ Morphological Exploration
⚠ Did you mean…
Cache: —
LLM: —
Kaitiaki: —
Morphological Cross-Pollination
LOG4 Base-5 butterfly seed analysis
Select a candidate and click Cross-Pollinate
⚗️
No seed molecule — scaffold exploration mode
Parliament will first query ChEMBL and ZINC for known actives against your target. If the databases return useful hits, those become your starting scaffolds — grounded in real chemistry.

If nothing comes back, Parliament will generate structurally drug-like candidates that pass property filters (MW, logP, Lipinski) but have no confirmed activity against your target yet.

This is useful for exploring chemical space and identifying scaffolds worth investigating — but these results are not suitable for wet lab prioritisation without further validation against your specific target.
Candidate